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XEOMIN® - The New Generation Pure Toxin

ZERO IMPURITIES* = LOWER RISK OF NEUTRALISING ANTIBODY FORMATION

The Pure+ botulinum toxin comes without impurities*, making it effective after every treatment. This lowers the risk of developing botulin um toxin resistance1, 2, one of the main causes of declining treatment effects. Using a state-of-the-art double purification process that effectively removes all impurities*, leaving only the active neurotoxin molecule to lower your risk of developing botulinum toxin resistance, the pure+ botulinum toxin treatment with zero impurities* delivers optimised results for each and every one of your beauty-enhancing treatments over time.

WHAT DOES ZERO IMPURITIES* IN THE PURE TOXIN MEAN FOR YOU?
Zero Impurities*= Lower risk of neutralizing anibody formation
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Efficacy is a clinically proven.
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Reduced risk of Botulinum Toxin Resistance.
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0ptimal results with every treatment.
State-of-the-art Manufacturing Process

XEOMIN® is made through a unique precision manufacturing process called XTRACT TechnologyTM by Merz, that uses two filtration steps to isolate the therapeutic component of the molecule and removes the complexing/unnecessary proteins that don’t play an active role in treatment.

Impurity*
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XEOMIN® is a double-filtered neurotoxin. Head-to-head studies evaluating the relative risk of immunogenicity due to the presence or absence of complexing/unnecessary proteins have not been performed.

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Clinical Proven

  • Botulinum toxin type A injection has been the most common cosmetic procedure in the United States for over 10 years.

  • XEOMIN® is approved by the US Food and Drug Administration (US FDA), UK MHRA, The Federal Institute for Drugs and Medical Devices in Germany and the Hong Kong Department of Health.

  • XEOMIN® has been approved for aesthetic use in more than 40 countries worldwide.

  • XEOMIN® provides the full benefits of Botulinum Toxin with lower risk of antibody formation that may cause toxin resistance during repeat treatments.1

  • Over 98% of XEOMIN® users sees improvements after XEOMIN® treatment.3

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* Impurities include complex proteins, inactive neurotoxins, flagellin, and bacterial DNA. 1,2
+ Pure means free of complex proteins, inactive neurotoxins, flagellin and bacterial DNA. 1,2
^ Compared with other Hong Kong registered brands. 1,2
1. Park JY et al. Neurotoxin impurities: A Review of threats to Efficacy. Plast Recontr Surg Glob Open. 2020:8(1)e2627
2. Kerscher M, et al. A Highly Purified and Precisely Manufactured Botulinum Neurotoxin Type A. J Drugs Dermatol. 2019 Jan 1:18(1):52-57
3. Prager Wet al. Clin Intery Aging.2013;8:449-456
4. Approved Product Information. Aug 2021.
5. American Society of Plastic Surgeons. (2015) Plastic Surgery Procedural Statistics 2004-2014. Retrieved November 18. 2016, from American Society of Plastic Surgeons.
http://www.plasticsurgery.org/news/plastic-surgery-statistics.html
6. Rzany B, et al. Long-term results for in the treatment of glabellar frown lines. . 2013 Jan: 39(1 Pt 1):95-103
7. Imhof M, Kühne U. A Phase ilI Study of in the Treatment of Glabellar Frown Lines. 2011; 4(10):28-34
8. Prager W, et al. Onset, longevity, and patient satisfaction with for the treatment of glabellar frown lines: a single-arm, prospective clinical study. 2013;8:449-56
9. Rappi T, et al. Onset and Duration of Effect of and AbobotulinumtoxinA in the Treatment of Glabellar Frown Lines: A Randomized, Double Blind Study. 2013 Sep 24: 6:211-19.

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